Published on September 21, 2012 at 9:15 AM
By Lynda Williams, senior medwireNews Reporter
Pooled data from eight hospitals in England shows that patients given low molecular weight heparin (LMWH) had a significantly lower rate of wound complications in the 30 days after surgery than those treated with the oral anticoagulant rivaroxaban, at 2.81% versus 3.86% and an odds ratio (OR) of 0.72.
The rate of return to surgery to treat wound complications did not significantly differ by treatment, but patients with wound complications ‑ defined as hematoma or superficial or deep infection ‑ had a significantly longer stay on average than those without, at 14.2 versus 6.6 days.
However, patients given rivaroxaban were significantly less likely to develop symptomatic deep vein thrombosis than their LMWH-treated counterparts (0.23 vs 0.91%), report Simon Jameson (James Cook University Hospital, Middlesbrough, UK) and co-authors.
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